Short- and long-term mechanical circulatory support devices have been increasing in use the last decade in acute and chronic heart failure. Therapeutic modulation of circulating adhesion molecules may be of benefit to the patients outcome and therefore warrants further study. Trauma patients showed lower plasma levels of circulating adhesion molecules than did sepsis patients indicating more pronounced (inflammatory related) endothelial activation or damage in sepsis. Adhesion molecules are considered to be a cornerstone in this process. All non-survivors showed sICAM-1 plasma levels of > 800 ng/ml.Įndothelial damage may result in multiple-organ dysfunction syndrome. In the septic patients, sICAM-1 increased further (2,022 +/- 609 ng/ml) and remained unchanged in the trauma group. sICAM-1 was elevated in both groups at baseline and was higher in the sepsis group (1,266 +/- 261 ng/ml) than in the trauma group.
Non-survivors showed markedly elevated plasma levels of sELAM-1 and sVCAM-1. In the sepsis patients, sELAM-1 significantly decreased and sVCAM-1 increased, but remained almost unchanged in the trauma patients. In the trauma group, sELAM-1 (57.9 +/- 11.0 ng/ml) and sVCAM-1 (698 +/- 93 ng/ml) were within normal ranges at baseline, whereas they were markedly elevated in the sepsis group (sELAM-1: 340 +/- 95 ng/ml sVCAM-1 1,042 +/- 449 ng/ml). Kabonde says the police has since written to the Director of Public Prosecution (DPP) for consent to prosecute the 280 that were earlier arrested.The time course of circulating adhesion molecules was monitored in traumatized and sepsis patients.Ī surgical intensive care unit of a university hospital.Ī total of 30 consecutive critically ill patients suffering either from trauma (n = 15) or postoperative sepsis (n = 15).Īll patients were on continuous analgo-sedation and mechanical ventilation.įrom arterial blood samples, plasma levels of soluble adhesion molecules, and vascular cell adhesion molecule-1 (sVCAM-1) were measured on the day of admission (trauma patients) or on the day of diagnosis of sepsis (= baseline values), and during the following 5 days. Inspector General of police Francis Kabonde has appealed to Mansa residents who were involved in the looting to surrender themselves to police.Īfter the riots the police recovered goods worth billions of Kwacha.Īnd Mr. Siamana disclosed that the police have since launched an investigation over the same incident to ascertain who were involved in the killing.Īnd 60 more people have been arrested by the Zambia Police Service in connection with last week’s riots in Mansa. She has appealed to the general public to only arrest and take the suspects to the police. Siamana said the general public has the right to arrest but not to take the law in their own hands by taking away people’s lives.
Siamana said the two suspected criminals were identified as Kelvin Muyambango and Kelvin Sindengwe both aged between 30 and 35 years and their bodies are still lying in the mortuary. Zambia Police spokesperson Ndandula Siamana disclosed the development to ZANIS in a telephone interview in Lusaka today. The suspected criminals wanted to robe a house in Kanyama compound but the owner of a house who was alert switched on the alarm and the neighbors rushed to the house for rescue and managed to apprehend two criminals who later were stoned to death. Two suspected criminals were during the Easter period stoned to death by a mob in Lusaka’s Kanyama compound while the other three managed to escape. Zambia Police spokesperson Ndandula Siamana
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